| 18:00 | | | |
 Alabama | @ |  Wisconsin | 42-10 |
| 18:00 | | | |
 Oklahoma State | @ |  Tulsa | 45-10 |
| 18:00 | | | |
 LSU | @ |  South Carolina | 36-33 |
| 18:00 | | | |
 Arkansas State | @ |  Michigan | 18-28 |
| 18:00 | | | |
 Central Michigan | @ |  Illinois | 9-30 |
| 18:00 | | | |
 Memphis | @ |  Florida State | 20-12 |
| 18:00 | | | |
 Louisiana Tech | @ |  NC State | 20-30 |
| 18:00 | | | |
 Cincinnati | @ |  Miami (OH) | 27-16 |
| 18:00 | | | |
 North Texas | @ |  Texas Tech | 21-66 |
| 18:45 | | | |
 Boston College | @ |  Missouri | 21-27 |
| 19:00 | | | |
| Massachussets | @ | Buffalo | 3-34 |
| 20:00 | | | |
| Coastal Carolina | @ | Temple | 28-20 |
| 21:30 | | | |
 Oregon | @ |  Oregon State | 49-14 |
| 21:30 | | | |
 Ball State | @ |  Miami (FL) | 0-62 |
| 21:30 | | | |
 Tulane | @ |  Oklahoma | 19-34 |
| 21:30 | | | |
 Notre Dame | @ |  Purdue | 66-7 |
| 21:30 | | | |
 Texas A&M | @ |  Florida | 33-20 |
| 21:30 | | | |
 Prairie View A&M | @ |  Michigan State | 0-40 |
| 21:30 | | | |
 Nevada | @ |  Minnesota | 0-27 |
| 21:30 | | | |
 Washington State | @ |  Washington | 24-19 |
| 21:30 | | | |
| VMI | @ |  Georgia Tech | 7-59 |
| 21:30 | | | |
 West Virginia | @ |  Pittsburgh | 34-38 |
| 22:00 | | | |
 Troy | @ |  Iowa | 21-38 |
| 22:15 | | | |
 UAB | @ |  Arkansas | 27-37 |
| 22:30 | | | |
 Utah | @ |  Utah State | 38-21 |
| 00:00 | | | |
 UConn | @ |  Duke | 21-26 |
| 00:00 | | | |
| North Carolina Central | @ |  North Carolina | 45-10 |
| 00:00 | | | |
 Virginia Tech | @ |  Old Dominion | 37-17 |
| 00:30 | | | |
 Ole Miss | @ |  Wake Forest | 40-6 |
| 01:00 | | | |
 UTSA | @ |  Texas | 6-57 |
| 01:00 | | | |
 Vanderbilt | @ |  Georgia State | 32-36 |
| 01:30 | | | |
 Georgia | @ |  Kentucky | 13-12 |
| 01:30 | | | |
| Northern Iowa | @ |  Nebraska | 3-34 |
| 01:30 | | | |
 New Mexico | @ |  Auburn | 19-45 |
| 01:30 | | | |
 Toledo | @ |  Mississippi State | 41-17 |
| 01:30 | | | |
 Indiana | @ |  UCLA | 42-13 |
| 01:30 | | | |
 Air Force | @ |  Baylor | 3-31 |
| 01:30 | | | |
 Colorado | @ |  Colorado State | 28-9 |
| 01:30 | | | |
 UCF | @ |  TCU | 35-34 |
| 01:30 | | | |
| Eastern Illinois | @ |  Northwestern | 7-31 |
| 01:45 | | | |
 Kent State | @ |  Tennessee | 0-71 |
| 02:00 | | | |
 Maryland | @ |  Virginia | 27-13 |
| 02:00 | | | |
 Rice | @ |  Houston | 7-33 |
| 03:00 | | | |
 BYU | @ |  Wyoming | 34-14 |
| 04:30 | | | |
 San Diego State | @ |  California | 10-31 |
